Description

1H-Indole-1-Carboxylic Acid, 5-(4-Methyl-1-Piperazinyl)-, 1,1-Dimethylethyl Ester is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular scaffolds. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new chemical entities and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of novel drug candidates, particularly for central nervous system (CNS) and oncology targets.
• Organic Synthesis Reagent: Used in complex multi-step synthetic routes to construct indole and piperazine-containing molecular frameworks.
• Chemical Research & Development: Serves as a versatile substrate for medicinal chemistry programs, structure-activity relationship (SAR) studies, and process chemistry optimization.
• Reference Standard: Employed as a high-purity analytical standard for method development and quality control in API manufacturing.

Basic Information

Product Name	1H-Indole-1-Carboxylic Acid, 5-(4-Methyl-1-Piperazinyl)-, 1,1-Dimethylethyl Ester
CAS No.	913388-48-4
Molecular Formula	C19H27N3O2
Molecular Weight	329.44 g/mol
Synonyms	tert-Butyl 5-(4-methylpiperazin-1-yl)-1H-indole-1-carboxylate; 5-(4-Methyl-1-piperazinyl)-1H-indole-1-carboxylic acid 1,1-dimethylethyl ester; 1-(tert-Butoxycarbonyl)-5-(4-methylpiperazin-1-yl)indole; Boc-5-(4-Methylpiperazino)indole; 913388-48-4; 5-(N-Methylpiperazino)-1H-indole-1-carboxylic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our production of 1H-Indole-1-Carboxylic Acid, 5-(4-Methyl-1-Piperazinyl)-, 1,1-Dimethylethyl Ester adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.