Description

5-[1-(tert-Butoxycarbonyl)Piperidine-4-Carbonylamino]Indole is a high-purity, advanced pharmaceutical intermediate featuring a protected piperidine-indole scaffold. This compound is critical for medicinal chemistry research and development, enabling the synthesis of novel bioactive molecules. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of new therapeutic agents, particularly in the areas of central nervous system (CNS) and oncology drug discovery.

Application

• Key building block in the research and synthesis of novel pharmaceutical compounds.
• Intermediate for the development of potential drug candidates targeting neurological disorders.
• Precursor in the preparation of complex molecules for oncology research applications.
• Used in medicinal chemistry for structure-activity relationship (SAR) studies.
• Essential reagent in the synthesis of peptidomimetics and other bioactive scaffolds.
• Critical component in the development of kinase inhibitors and other enzyme-targeted therapies.

Basic Information

Product Name	5-[1-(tert-Butoxycarbonyl)Piperidine-4-Carbonylamino]Indole
CAS No.	913388-34-8
Molecular Formula	C19H25N3O3
Molecular Weight	343.42 g/mol
Synonyms	5-[(1-Boc-piperidin-4-yl)carbonylamino]indole; 5-[(1-(tert-Butoxycarbonyl)-4-piperidinyl)carbonylamino]-1H-indole; 1H-Indole-5-carboxamide, N-[1-[(1,1-dimethylethoxy)carbonyl]-4-piperidinyl]-; Boc-4-piperidinecarboxamide-indole derivative; tert-Butyl 4-[(1H-indol-5-yl)carbamoyl]piperidine-1-carboxylate
EINECS	Contact for details

Quality Control

Our 5-[1-(tert-Butoxycarbonyl)Piperidine-4-Carbonylamino]Indole is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP guidelines where applicable, and our analytical methods, including HPLC, NMR, and MS, are validated to provide reliable specifications for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.