Description

4-(5-Cyanothien-2-Yl)-6-Methylpyrimidin-2-Amine is a high-purity heterocyclic organic compound featuring a pyrimidine core substituted with a cyanothiophene moiety. This specialized chemical building block is critical for advanced research and development in medicinal chemistry, enabling the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories, agrochemical innovators, and fine chemical manufacturers seeking to develop new therapeutic agents and functional materials.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of kinase inhibitors and other small-molecule drug candidates.
• Agrochemical Research: Used in the synthesis of novel herbicides and fungicides with targeted modes of action.
• Material Science: Serves as a building block for organic electronic materials, such as semiconductors and light-emitting diodes (OLEDs).
• Chemical Biology: Employed as a molecular probe or scaffold in biochemical assay development and target identification.
• Academic & Contract Research: Essential for fundamental organic synthesis research and custom synthesis projects in CROs (Contract Research Organizations).

Basic Information

Product Name	4-(5-Cyanothien-2-Yl)-6-Methylpyrimidin-2-Amine
CAS No.	913322-64-2
Molecular Formula	C10H8N4S
Molecular Weight	216.26 g/mol
Synonyms	2-Amino-6-methyl-4-(5-cyanothiophen-2-yl)pyrimidine; 4-(5-Cyanothiophen-2-yl)-6-methylpyrimidin-2-amine; 6-Methyl-4-(5-cyanothiophen-2-yl)pyrimidin-2-amine; 913322-64-2; 4-(5-Cyano-2-thienyl)-6-methyl-2-pyrimidinamine; 4-(5-Cyanothien-2-yl)-6-methyl-2-pyrimidinamine
EINECS	Contact for details

Quality Control

Our 4-(5-Cyanothien-2-Yl)-6-Methylpyrimidin-2-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specifications and test results. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if necessary to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.