Description

2-(5-Fluoro-1H-Indol-3-Yl)-2-Oxoacetic Acid is a high-purity fluorinated indole derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its core value lies in providing a versatile, functionalized scaffold for constructing complex molecules, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries who require reliable building blocks for drug discovery programs.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Medicinal Chemistry Research: Used as a versatile building block for structure-activity relationship (SAR) studies and lead optimization in drug discovery.
• Active Pharmaceutical Ingredient (API) Synthesis: Employed in the multi-step synthesis of complex APIs containing the 5-fluoroindole pharmacophore.
• Agrochemical Development: Intermediate for creating novel herbicides, fungicides, or plant growth regulators with enhanced activity.
• Biochemical Probe Synthesis: Used to develop labeled compounds or probes for biological and pharmacological studies.
• Fine Chemical Manufacturing: Serves as a specialized intermediate for custom synthesis and contract manufacturing organizations (CMOs).

Basic Information

Product Name	2-(5-Fluoro-1H-Indol-3-Yl)-2-Oxoacetic Acid
CAS No.	913320-96-4
Molecular Formula	C10H6FNO3
Molecular Weight	207.16 g/mol
Synonyms	5-Fluoro-3-indoleglyoxylic acid; 2-Oxo-2-(5-fluoro-1H-indol-3-yl)acetic acid; (5-Fluoro-1H-indol-3-yl)-oxoacetic acid; 5-Fluoroindole-3-glyoxylic acid; α-Oxo-5-fluoro-1H-indole-3-acetic acid; 913320-96-4; 5-Fluoro-1H-indole-3-glyoxylic acid
EINECS	Contact for details

Quality Control

Our 2-(5-Fluoro-1H-Indol-3-Yl)-2-Oxoacetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed specifications are provided with every shipment to guarantee traceability, consistency, and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and performance. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.