Description

4-Fluoro-7-Nitro 1H-Indole-2-Ethyl Carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its unique indole scaffold substituted with fluorine and nitro groups. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of novel drug candidates with targeted biological activity. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly in oncology and CNS research.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of complex indole-based active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Fluorinated Compound Synthesis: The fluorine atom makes it valuable for creating fluorinated analogs to improve metabolic stability and bioavailability of lead compounds.
• Agrochemical Research: Potential use in the development of new herbicides or fungicides leveraging the bioactive indole structure.
• Material Science: Can be investigated as a monomer or precursor for specialty polymers and organic electronic materials.

Basic Information

Product Name	4-Fluoro-7-Nitro 1H-Indole-2-Ethyl Carboxylate
CAS No.	913287-14-6
Molecular Formula	C11H9FN2O4
Molecular Weight	252.20 g/mol
Synonyms	Ethyl 4-Fluoro-7-nitro-1H-indole-2-carboxylate; 1H-Indole-2-carboxylic acid, 4-fluoro-7-nitro-, ethyl ester; 4-Fluoro-7-nitroindole-2-carboxylic acid ethyl ester; 913287-14-6; 4-Fluoro-7-nitro-1H-indole-2-carboxylic acid ethyl ester; Ethyl 4-fluoro-7-nitroindole-2-carboxylate; 2-Carbethoxy-4-fluoro-7-nitroindole
EINECS	Contact for details

Quality Control

Our 4-Fluoro-7-Nitro 1H-Indole-2-Ethyl Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.