Description

Cenobamate S-Enantiomer is the single, pharmacologically active stereoisomer of the novel anti-seizure medication cenobamate. This high-purity enantiomer is critical for advanced pharmaceutical research and development, particularly in studying receptor-specific mechanisms and developing next-generation therapeutics. It is primarily utilized by pharmaceutical companies, contract research organizations (CROs), and academic institutions engaged in neurology-focused drug discovery, process chemistry, and analytical method development.

Application

• Active Pharmaceutical Ingredient (API) Intermediate: Serves as a key chiral building block in the synthesis of cenobamate and its derivatives.
• Pharmacological Research: Used in in vitro and in vivo studies to investigate the specific biological activity and metabolic profile of the S-enantiomer.
• Analytical Reference Standard: Employed as a high-purity standard for HPLC, LC-MS, and chiral chromatography methods for quality control and impurity profiling.
• Process Development & Optimization: Aids in the development and scaling of stereoselective synthesis routes for improved yield and purity.
• Formulation Studies: Supports pre-formulation research for novel drug delivery systems targeting neurological conditions.
• Regulatory Submissions: Provides well-characterized material for inclusion in regulatory documentation (e.g., IND, NDA) to support drug approval processes.

Basic Information

Product Name	Cenobamate S-Enantiomer
CAS No.	913088-81-0
Molecular Formula	C10H10FN3O2
Molecular Weight	223.20 g/mol
Synonyms	(S)-2-(2-Chlorophenyl)-2-hydroxyethyl carbamate; (S)-2-(2-Chlorophenyl)-2-hydroxyethyl carbamate; (S)-Cenobamate; (S)-YKP3089; (2S)-2-(2-Chlorophenyl)-2-hydroxyethyl carbamate; UNII-8K713B0Y5U; (S)-2-Hydroxy-2-(2-chlorophenyl)ethyl carbamate
EINECS	Contact for details

Quality Control

Our Cenobamate S-Enantiomer is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assay, identification, and impurity profiling by HPLC and other validated methods, to ensure it meets stringent specifications for pharmaceutical research. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance with your quality requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider storing under inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.5%
Chiral Purity (HPLC)	≥99.0% (S-Enantiomer)
Related Substances (HPLC)	Total impurities ≤1.5% Any single impurity ≤0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.