Description

Ethosuximide is a high-purity pharmaceutical active ingredient, primarily recognized for its anticonvulsant properties. Its consistent quality and reliable performance are critical for ensuring the safety and efficacy of final pharmaceutical formulations. This compound is essential for manufacturers in the pharmaceutical industry, particularly those developing and producing anti-epileptic medications for the treatment of absence seizures.

Application

• Pharmaceutical Active Ingredient (API): The primary application is as the key therapeutic component in anti-epileptic drugs, specifically for controlling absence (petit mal) seizures.
• Neurological Disorder Research: Used as a reference standard and active compound in preclinical and clinical research focused on seizure disorders and neural excitability.
• Formulation Development: Employed in the R&D of solid oral dosage forms, such as capsules and syrups, requiring precise and stable API integration.
• Analytical Reference Standard: Serves as a high-purity certified reference material (CRM) for quality control testing, method validation, and regulatory submissions.
• Generic Drug Manufacturing: A critical raw material for companies producing bioequivalent generic versions of ethosuximide-based medications.

Basic Information

Product Name	Ethosuximide
CAS No.	77-67-8
Molecular Formula	C7H11NO2
Molecular Weight	141.17 g/mol
Synonyms	2-Ethyl-2-methylsuccinimide; 3-Ethyl-3-methylpyrrolidine-2,5-dione; Zarontin®; Emeside; Petinimid; Suxinutin; Ethymal; PM 671
EINECS	201-048-7

Quality Control

Our Ethosuximide is manufactured and tested under strict quality management systems to ensure it meets the stringent requirements of the pharmaceutical industry. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We can supply material compliant with various pharmacopeial standards, including USP and EP, upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.0% - 102.0%
Related Substances (HPLC)	Individual impurity: NMT 0.5% Total impurities: NMT 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	< 20 ppm
Loss on Drying	< 0.5%
Sulfated Ash	< 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.