Description

5,5-Diphenylhydantoin Calcium is the calcium salt derivative of the anticonvulsant agent phenytoin. This compound is valued for its enhanced stability and specific formulation properties compared to the free acid form. It is primarily utilized in the pharmaceutical industry for the research, development, and production of specialized drug formulations. The product is supplied under the CAS registry number 17149-74-5.

Application

• Pharmaceutical Intermediate: A key starting material or intermediate in the synthesis of advanced active pharmaceutical ingredients (APIs) and their derivatives.
• Reference Standard: Used as a certified reference material (CRM) in analytical laboratories for method development, validation, and quality control testing.
• Neurological Research: Employed in preclinical and biochemical research studies investigating mechanisms of action related to sodium channel blockade and seizure control.
• Formulation Excipient: Can serve as a stabilizing agent or counterion in specific solid-dosage and parenteral drug formulations requiring calcium salts.
• Chemical Synthesis: Acts as a building block for the preparation of more complex hydantoin-based compounds for various therapeutic applications.

Basic Information

Product Name	5,5-Diphenylhydantoin Calcium
CAS No.	17149-74-5
Molecular Formula	C30H22CaN4O4
Molecular Weight	542.61 g/mol
Synonyms	Calcium 5,5-Diphenylhydantoin; Phenytoin Calcium Salt; 5,5-Diphenyl-2,4-imidazolidinedione Calcium Salt; NSC 52923; Calcium Diphenylhydantoinate; Diphenylhydantoin Calcium; Phenytoin Ca; Calcium Phenytoin
EINECS	241-212-8

Quality Control

Our 5,5-Diphenylhydantoin Calcium is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and support our products with detailed Certificates of Analysis (COA), which are available upon request. Specifications are designed to meet the rigorous demands of pharmaceutical research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 2.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	10.0% - 12.0% (as CaO)
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.