Description

5-Chloroisoindoline Hydrochloride is a high-purity organic building block essential for advanced pharmaceutical and agrochemical research. This compound serves as a critical intermediate in the synthesis of complex molecules, particularly those targeting specific biological pathways. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and oncology targets.
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Used in the preparation of specialized ligands for metal-catalyzed cross-coupling reactions.
• Material Science Research: Intermediate for creating organic semiconductors, dyes, and photoactive polymers.
• Chemical Biology Probes: Serves as a scaffold for developing molecular probes and diagnostic agents.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs for the production of client-specific compounds under cGMP conditions.

Basic Information

Product Name	5-Chloroisoindoline Hydrochloride
CAS No.	912999-79-2
Molecular Formula	C8H9Cl2N
Molecular Weight	190.07 g/mol
Synonyms	5-Chloro-2,3-dihydro-1H-isoindole hydrochloride; 5-Chloro-isoindoline HCl; 5-Chloro-1H-isoindole, 2,3-dihydro-, hydrochloride; Isoindoline, 5-chloro-, hydrochloride; 5-Chloroisoindolinium chloride
EINECS	Contact for details

Quality Control

Our 5-Chloroisoindoline Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and stringent control of residual solvents and heavy metals. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment to ensure compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.