Description

6-(Piperidin-4-Yl)Indoline is a versatile heterocyclic building block featuring a fused indoline and piperidine scaffold. This compound is of significant value in pharmaceutical research and development due to its privileged structure, which is commonly found in bioactive molecules targeting the central nervous system and other therapeutic areas. It is primarily utilized by medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of novel active compounds and intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in neurological and psychiatric disorders.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in hit-to-lead optimization.
• Ligand Synthesis: Used in the preparation of complex ligands for catalysis or receptor binding studies.
• Agrochemical Research: Employed as a building block in the discovery of new active ingredients for crop protection.
• Chemical Biology Probes: Functionalized to create tool compounds for studying biological pathways and target validation.
• Process Chemistry: Investigated for scalable synthesis routes in the production of advanced pharmaceutical intermediates (APIs).

Basic Information

Product Name	6-(Piperidin-4-Yl)Indoline
CAS No.	912999-76-9
Molecular Formula	C13H18N2
Molecular Weight	202.30 g/mol
Synonyms	4-(2,3-Dihydro-1H-indol-6-yl)piperidine; 6-(4-Piperidyl)indoline; 6-Piperidin-4-yl-2,3-dihydro-1H-indole; 1H-Indole, 6-(4-piperidinyl)-2,3-dihydro-; 6-(Piperidin-4-yl)-2,3-dihydro-1H-indole
EINECS	Contact for details

Quality Control

Our 6-(Piperidin-4-Yl)Indoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the exacting standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are provided to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.