Description

n-(3-Bromophenyl)-4-Chlorothiazol-2-Amine CAS NO 912969-58-5 is a high-purity, halogenated heterocyclic amine building block of significant importance in advanced organic synthesis. This compound matters because it serves as a critical intermediate for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate functionalized thiazole motifs into their target molecules.

Application

• Key synthetic intermediate in the research and development of novel pharmaceutical compounds, particularly kinase inhibitors and other small-molecule therapeutics.
• Building block for the synthesis of advanced agrochemicals, including herbicides, fungicides, and insecticides, leveraging the bioactivity of the thiazole core.
• Precursor in material science for the development of organic electronic materials and functional polymers.
• Versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Intermediate for producing dyes and pigments with specific light-fastness and color properties.
• Used in academic and industrial research as a model compound for studying cross-coupling and heterocyclic substitution reactions.

Basic Information

Product Name	n-(3-Bromophenyl)-4-Chlorothiazol-2-Amine
CAS No.	912969-58-5
Molecular Formula	C9H6BrClN2S
Molecular Weight	289.58 g/mol
Synonyms	4-Chloro-N-(3-bromophenyl)-1,3-thiazol-2-amine; 2-Amino-4-chloro-5-(3-bromophenyl)thiazole; 4-Chloro-2-((3-bromophenyl)amino)thiazole; N-(3-Bromophenyl)-4-chloro-2-thiazolamine; 912969-58-5; 4-Chloro-N-(3-bromophenyl)thiazol-2-amine
EINECS	Contact for details

Quality Control

Our n-(3-Bromophenyl)-4-Chlorothiazol-2-Amine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, supporting its use in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.