Description

7-Fluoro-6-Nitro-1,2,3,4-Tetrahydroisoquinoline is a high-purity, advanced pharmaceutical intermediate characterized by its unique fused-ring structure. This compound is a critical building block in modern organic synthesis, valued for its role in constructing complex molecules with targeted biological activity. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs), particularly within medicinal chemistry programs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery.
• Agrochemical Synthesis: Used in the research and development of new generation pesticides and herbicides, leveraging its nitro and fluorine substituents.
• Organic Synthesis Building Block: Employed in academic and industrial laboratories for the construction of complex heterocyclic compounds and fine chemicals.
• Biochemical Tool Compound: Potential use in developing probes and inhibitors for biochemical and pharmacological research.

Basic Information

Item	Details
Product Name	7-Fluoro-6-Nitro-1,2,3,4-Tetrahydroisoquinoline
CAS No.	912878-83-2
Molecular Formula	C9H9FN2O2
Molecular Weight	196.18 g/mol
Synonyms	7-Fluoro-6-nitro-1,2,3,4-tetrahydroisoquinoline; 6-Nitro-7-fluoro-1,2,3,4-tetrahydroisoquinoline; 1,2,3,4-Tetrahydro-7-fluoro-6-nitroisoquinoline; 7-Fluoro-6-nitro-3,4-dihydro-1H-isoquinoline; FNTIQ; 912878-83-2; 7-Fluoro-6-nitro-THIQ
EINECS	Contact for details

Quality Control

Our 7-Fluoro-6-Nitro-1,2,3,4-Tetrahydroisoquinoline is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and industry best practices for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere). Keep container tightly sealed under an inert atmosphere such as nitrogen or argon for long-term storage to maintain optimal purity.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.