Description

1-(2-Thiophen-2-Yl-Imidazo[1,2-A]Pyrimidin-3-Ylmethyl)-Piperidine-3-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of novel active pharmaceutical ingredients (APIs). This heterocyclic compound is critical for research and development in medicinal chemistry, offering a complex molecular scaffold for targeted drug discovery. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing new therapeutic agents, particularly in areas requiring sophisticated nitrogen-containing heterocycles.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and anti-infective targets.
• Medicinal Chemistry Research: Used as a core scaffold in structure-activity relationship (SAR) studies to optimize potency and selectivity of lead compounds.
• Biochemical Tool Compound: Employed in biochemical assays to study enzyme inhibition or receptor modulation due to its fused imidazopyrimidine structure.
• Fine Chemical Synthesis: Acts as a precursor for the preparation of more complex, functionalized molecules in custom synthesis projects.
• Academic Research: Utilized in university and institutional labs for investigating new synthetic methodologies involving thiophene and imidazopyrimidine motifs.

Basic Information

Product Name	1-(2-Thiophen-2-Yl-Imidazo[1,2-A]Pyrimidin-3-Ylmethyl)-Piperidine-3-Carboxylic Acid
CAS No.	912770-78-6
Molecular Formula	C17H18N4O2S
Molecular Weight	342.42 g/mol
Synonyms	1-[(2-Thiophen-2-ylimidazo[1,2-a]pyrimidin-3-yl)methyl]piperidine-3-carboxylic acid; 1-((2-(Thiophen-2-yl)imidazo[1,2-a]pyrimidin-3-yl)methyl)piperidine-3-carboxylic acid; Piperidine-3-carboxylic acid, 1-[(2-(2-thienyl)imidazo[1,2-a]pyrimidin-3-yl)methyl]-; UNII-9F6X7V6A8I; 9F6X7V6A8I; 912770-78-6; 1-(2-Thiophen-2-yl-imidazo[1,2-a]pyrimidin-3-ylmethyl)-piperidine-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our 1-(2-Thiophen-2-Yl-Imidazo[1,2-A]Pyrimidin-3-Ylmethyl)-Piperidine-3-Carboxylic Acid is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. We adhere to current Good Manufacturing Practices (cGMP) where applicable for pharmaceutical intermediates. Comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, is performed. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.