Description

Carbamic Acid, [4-[[(7-Chloro-3-Isoquinolinyl)Carbonyl]Amino]-1-Formyl-3-Piperidinyl]-, 1,1-Dimethylethyl Ester (9Ci) is a sophisticated, high-purity chemical intermediate featuring a complex molecular architecture combining isoquinoline and piperidine motifs. This compound is of significant value in pharmaceutical research and development, particularly for its potential role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and pharmaceutical companies engaged in medicinal chemistry, process development, and the discovery of new therapeutic agents targeting a range of diseases.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of complex drug candidates, especially those targeting central nervous system (CNS) disorders, oncology, or infectious diseases.
• Medicinal Chemistry Research: Used as a scaffold or building block for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Process Chemistry Development: Employed in the optimization and scale-up of synthetic routes for potential new chemical entities (NCEs).
• Biochemical Research: May be utilized in the development of enzyme inhibitors or receptor modulators due to its specific structural features.
• Custom Synthesis & Contract Manufacturing: A key material for fine chemical suppliers offering bespoke synthesis services to the pharmaceutical industry.

Basic Information

Product Name	Carbamic Acid, [4-[[(7-Chloro-3-Isoquinolinyl)Carbonyl]Amino]-1-Formyl-3-Piperidinyl]-, 1,1-Dimethylethyl Ester (9Ci)
CAS No.	912481-97-1
Molecular Formula	C21H25ClN4O4
Molecular Weight	432.90 g/mol
Synonyms	tert-Butyl (4-((7-chloroisoquinoline-3-carbonyl)amino)-1-formylpiperidin-3-yl)carbamate; 1,1-Dimethylethyl N-[4-[[(7-chloro-3-isoquinolinyl)carbonyl]amino]-1-formyl-3-piperidinyl]carbamate; 912481-97-1; Carbamic acid, N-[4-[[(7-chloro-3-isoquinolinyl)carbonyl]amino]-1-formyl-3-piperidinyl]-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

This high-value intermediate is produced under strict quality control protocols to ensure batch-to-batch consistency and purity suitable for research and development applications. Our quality system employs advanced analytical techniques including HPLC, NMR, and MS for comprehensive characterization. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture uptake, which may affect stability and handling properties. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.