Description

2-([1,1'-Biphenyl]-4-Ylacetyl)-1,2,3,4-Tetrahydro-6,7-Dimethoxy-Isoquinoline is a high-purity, synthetic organic compound belonging to the isoquinoline class, serving as a critical advanced pharmaceutical intermediate. Its complex molecular architecture makes it a valuable building block for the research and development of novel active pharmaceutical ingredients (APIs). This compound is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of complex molecules for therapeutic applications.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of potential drug candidates, particularly in central nervous system (CNS) and cardiovascular research.
• Chemical Research & Development: Used as a sophisticated scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Academic Research: Employed in university and institutional labs for studying heterocyclic chemistry, reaction mechanisms, and the synthesis of complex natural product analogs.
• Process Development: Serves as a model compound for developing and scaling up novel synthetic routes under current Good Manufacturing Practice (cGMP) guidelines.

Basic Information

Product Name	2-([1,1'-Biphenyl]-4-Ylacetyl)-1,2,3,4-Tetrahydro-6,7-Dimethoxy-Isoquinoline
CAS No.	912350-27-7
Molecular Formula	C25H25NO3
Molecular Weight	387.47 g/mol
Synonyms	2-([1,1'-Biphenyl]-4-ylacetyl)-1,2,3,4-tetrahydro-6,7-dimethoxyisoquinoline; 2-(4-Biphenylylacetyl)-1,2,3,4-tetrahydro-6,7-dimethoxyisoquinoline; 6,7-Dimethoxy-2-[(1,1'-biphenyl-4-yl)acetyl]-1,2,3,4-tetrahydroisoquinoline; Biphenyl-4-ylacetyl-tetrahydrodimethoxyisoquinoline; THIQ derivative 912350-27-7
EINECS	Contact for details

Quality Control

Our production of 2-([1,1'-Biphenyl]-4-Ylacetyl)-1,2,3,4-Tetrahydro-6,7-Dimethoxy-Isoquinoline adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the exacting standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting purity, related substances, and other critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.