Description

3-(2-Hydroxy-1-Phenyl-Ethyl)-1H-Indole-5-Carbonitrile is a specialized indole-based chemical building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of complex molecules, particularly in the pharmaceutical sector. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly those targeting neurological and oncological pathways.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its indole core structure.
• Organic Light-Emitting Diode (OLED) Materials: Serves as a precursor for electron-transport or emissive layer materials in electronic displays.
• Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Fluorescent Probe Development: The indole-carbonitrile structure is useful for creating sensors and bio-imaging agents.
• Academic & Contract Research: A valuable reagent for methodological studies and custom synthesis projects in university and CRO laboratories.

Basic Information

Product Name	3-(2-Hydroxy-1-Phenyl-Ethyl)-1H-Indole-5-Carbonitrile
CAS No.	911104-50-2
Molecular Formula	C₁₇H₁₄N₂O
Molecular Weight	262.31 g/mol
Synonyms	5-Cyano-3-(2-hydroxy-1-phenylethyl)indole; 1H-Indole-5-carbonitrile, 3-(2-hydroxy-1-phenylethyl)-; 3-(2-Hydroxy-1-phenylethyl)-1H-indole-5-carbonitrile; 3-(α-Hydroxybenzyl)-1H-indole-5-carbonitrile; 3-(2-Hydroxy-2-phenylethyl)-1H-indole-5-carbonitrile; 5-CN-3-(HO-CH(Ph)-CH2)-Indole; CAS 911104-50-2
EINECS	Contact for details

Quality Control

Our 3-(2-Hydroxy-1-Phenyl-Ethyl)-1H-Indole-5-Carbonitrile is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent identity. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to prevent moisture absorption, which may affect stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.