Description

4-Chlorothiophene-2-Carbonitrile is a versatile and high-value heterocyclic building block used in advanced organic synthesis. This compound matters as a key precursor for the development of novel pharmaceuticals, agrochemicals, and functional materials due to its reactive nitrile and halogen substituents on the thiophene ring. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Serves as a building block for developing new generation herbicides, fungicides, and insecticides with enhanced efficacy.
• Material Science: Used in the research and production of conductive polymers, organic semiconductors, and non-linear optical (NLO) materials.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for transition metal catalysis and organocatalysts.
• Chemical Research: A valuable reagent for heterocyclic chemistry exploration, including ring-forming reactions and functional group transformations.
• Dye and Pigment Intermediate: Acts as a precursor for synthesizing specialized thiophene-based dyes and colorants.

Basic Information

Product Name	4-Chlorothiophene-2-Carbonitrile
CAS No.	910553-55-8
Molecular Formula	C5H2ClNS
Molecular Weight	143.59 g/mol
Synonyms	2-Cyano-4-chlorothiophene; 4-Chloro-2-thiophenecarbonitrile; 4-Chlorothiophene-2-carbonitrile; 4-Chloro-2-cyanothiophene; 2-Thiophenecarbonitrile, 4-chloro-; Thiophene-2-carbonitrile, 4-chloro-
EINECS	Contact for details

Quality Control

Our 4-Chlorothiophene-2-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency suitable for research and scale-up applications. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.