Description

1-Acetyl-n-([6-(Trifluoromethyl)Pyridin-3-Yl]Methyl)Indolin-7-Amine is a high-purity, advanced pharmaceutical intermediate characterized by its unique indoline and trifluoromethylpyridine hybrid structure. This compound is of significant value for medicinal chemistry research and development, particularly in the synthesis of novel bioactive molecules targeting a range of therapeutic areas. It is primarily sought after by R&D teams and process chemists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, especially for central nervous system (CNS) and oncology targets.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its privileged scaffold.
• Agrochemical Development: Serves as a precursor in the research of novel pesticides and herbicides, leveraging the biological activity of the trifluoromethylpyridine moiety.
• Ligand and Probe Synthesis: Utilized in creating specialized chemical probes for biochemical assays and diagnostic development.
• Fine Chemical Synthesis: Employed in custom synthesis and contract manufacturing for producing high-value, complex organic molecules.

Basic Information

Product Name	1-Acetyl-n-([6-(Trifluoromethyl)Pyridin-3-Yl]Methyl)Indolin-7-Amine
CAS No.	909666-31-5
Molecular Formula	C18H16F3N3O
Molecular Weight	347.34 g/mol
Synonyms	1-Acetyl-N-{[6-(trifluoromethyl)pyridin-3-yl]methyl}-2,3-dihydro-1H-indol-7-amine; 7-Amino-1-acetyl-N-[(6-trifluoromethyl-3-pyridyl)methyl]indoline; 1-Acetyl-7-({[6-(trifluoromethyl)pyridin-3-yl]methyl}amino)indoline; 909666-31-5; N-((6-(Trifluoromethyl)pyridin-3-yl)methyl)-1-acetylindolin-7-amine
EINECS	Contact for details

Quality Control

Our production of 1-Acetyl-n-([6-(Trifluoromethyl)Pyridin-3-Yl]Methyl)Indolin-7-Amine adheres to stringent quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and KF for moisture content, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with each shipment, guaranteeing traceability and consistent quality for your critical projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.