Description

1-Acetyl-n-([6-(Trifluoromethyl)Pyridin-3-Yl]Methyl)Indolin-6-Amine is a high-value, synthetically derived organic compound featuring a fused indoline and pyridine scaffold with a trifluoromethyl group. This specific molecular architecture makes it a critical advanced pharmaceutical intermediate (API intermediate) and a versatile building block in medicinal chemistry research. It is primarily sought after by R&D and production teams in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis due to its privileged heterocyclic structure.
• Agrochemical Active Ingredient Synthesis: Serves as a precursor in the development of new herbicides or insecticides, leveraging the bioactivity of the trifluoromethylpyridine moiety.
• Chemical Biology Probe Development: Utilized in the creation of molecular probes for studying enzyme function or biological pathways.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.

Basic Information

Product Name	1-Acetyl-n-([6-(Trifluoromethyl)Pyridin-3-Yl]Methyl)Indolin-6-Amine
CAS No.	909666-28-0
Molecular Formula	C18H16F3N3O
Molecular Weight	347.34 g/mol
Synonyms	1-ACETYL-N-{[6-(TRIFLUOROMETHYL)PYRIDIN-3-YL]METHYL}-2,3-DIHYDRO-1H-INDOLE-6-AMINE; 1-Acetyl-N-((6-(trifluoromethyl)pyridin-3-yl)methyl)-2,3-dihydro-1H-indol-6-amine; 6-Amino-1-acetyl-N-[(6-trifluoromethyl-3-pyridyl)methyl]indoline; N-((6-(Trifluoromethyl)pyridin-3-yl)methyl)-1-acetylindolin-6-amine; 909666-28-0; 1H-Indole-6-amine, 1-acetyl-N-((6-(trifluoromethyl)-3-pyridinyl)methyl)-2,3-dihydro-
EINECS	Contact for details

Quality Control

Our 1-Acetyl-n-([6-(Trifluoromethyl)Pyridin-3-Yl]Methyl)Indolin-6-Amine is produced under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure high purity and consistent identity, meeting the exacting standards required for pharmaceutical R&D. Comprehensive Certificates of Analysis (COA) documenting purity (HPLC), identity (IR, NMR), and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.