Description

8-Methoxy-2-([6-(Trifluoromethyl)Pyridin-3-Yl]Methyl)-1,2,3,4-Tetrahydropyrazino[1,2-A]Indole is a high-purity, complex heterocyclic compound designed for advanced research and development applications. This molecule is of significant interest due to its unique structural features, including a tetrahydropyrazinoindole core and a trifluoromethylpyridine moiety, which are valuable in modern synthetic chemistry. It serves as a critical pharmaceutical intermediate and building block for medicinal chemists and process development scientists working in drug discovery and fine chemical synthesis.

Application

This specialized chemical is utilized in sophisticated research and industrial processes. Key application areas include:

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and oncology targets.
• Medicinal Chemistry Research: Used as a core scaffold or building block for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Process Chemistry Development: Employed in route scouting, optimization, and scale-up studies for the commercial production of complex drug candidates.
• Biochemical Research: Acts as a ligand or probe in biochemical assays to study enzyme inhibition and receptor binding mechanisms.
• Fine Chemical Synthesis: Used in the multi-step synthesis of other high-value, complex organic molecules for agrochemical or material science applications.

Basic Information

Item	Details
Product Name	8-Methoxy-2-([6-(Trifluoromethyl)Pyridin-3-Yl]Methyl)-1,2,3,4-Tetrahydropyrazino[1,2-A]Indole
CAS No.	909661-37-6
Molecular Formula	C22H20F3N3O
Molecular Weight	399.41 g/mol
Synonyms	8-Methoxy-2-((6-(trifluoromethyl)pyridin-3-yl)methyl)-1,2,3,4-tetrahydropyrazino[1,2-a]indole; 1,2,3,4-Tetrahydropyrazino[1,2-a]indole, 8-methoxy-2-[[6-(trifluoromethyl)-3-pyridinyl]methyl]-; 8-Methoxy-2-((6-(trifluoromethyl)pyridin-3-yl)methyl)-3,4-dihydro-1H-pyrazino[1,2-a]indole; 909661-37-6; Pyrazino[1,2-a]indole derivative; Trifluoromethylpyridine-substituted tetrahydropyrazinoindole
EINECS	Contact for details

Quality Control

Our 8-Methoxy-2-([6-(Trifluoromethyl)Pyridin-3-Yl]Methyl)-1,2,3,4-Tetrahydropyrazino[1,2-A]Indole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports your R&D and cGMP-compliant development work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a desiccated environment and away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.