Description

Exo-3-Oxabicyclo[3.1.0]Hexane-6-Methanamine is a specialized bicyclic amine compound featuring a unique oxabicyclo[3.1.0]hexane scaffold. This high-purity building block is critical for advanced pharmaceutical research and development, particularly in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to incorporate its constrained, three-dimensional structure into new molecular entities.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of complex drug candidates, particularly those targeting the central nervous system (CNS).
• Medicinal Chemistry Research: Used in scaffold-hopping and structure-activity relationship (SAR) studies due to its rigid, three-dimensional geometry.
• Agrochemical Synthesis: Serves as a precursor for developing novel pesticides and herbicides with enhanced biological activity.
• Ligand and Catalyst Development: The amine functionality makes it a candidate for developing chiral ligands and organocatalysts for asymmetric synthesis.
• Fine Chemical Production: Employed in the multi-step synthesis of high-value specialty chemicals and advanced materials.
• Academic & Institutional R&D: Used in universities and research institutes for methodological studies in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	Exo-3-Oxabicyclo[3.1.0]Hexane-6-Methanamine
CAS No.	909406-64-0
Molecular Formula	C7H11NO
Molecular Weight	125.17 g/mol
Synonyms	6-(Aminomethyl)-3-oxabicyclo[3.1.0]hexane (exo-); exo-6-(Aminomethyl)-3-oxabicyclo[3.1.0]hexane; (1S,5R,6R)-6-(Aminomethyl)-3-oxabicyclo[3.1.0]hexane; (1R,5S,6S)-6-(Aminomethyl)-3-oxabicyclo[3.1.0]hexane; 3-Oxabicyclo[3.1.0]hexane-6-methanamine, exo-; Bicyclo[3.1.0]hexane-6-methanamine, 3-oxa-, exo-; Oxabicyclohexane Methanamine Derivative
EINECS	Contact for details

Quality Control

Our Exo-3-Oxabicyclo[3.1.0]Hexane-6-Methanamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis, to ensure it meets the high standards required for pharmaceutical R&D. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality commitment aligns with cGMP principles for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen) for long-term storage to prevent moisture uptake and degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.