Description

1H-Indole-5-Carboxylic Acid,6-Fluoro is a high-value fluorinated indole derivative, serving as a critical building block in advanced organic synthesis. Its core value lies in the strategic introduction of fluorine and a carboxylic acid functional group onto the indole scaffold, enabling precise modulation of molecular properties. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients with enhanced efficacy and metabolic stability.

Application

• Pharmaceutical Intermediate: A key synthon for the development of fluorinated drug candidates, particularly in oncology, CNS disorders, and anti-inflammatory therapies.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and plant growth regulators that benefit from the unique bioactivity of the fluorinated indole structure.
• Material Science Precursor: Employed in the creation of specialized organic electronic materials and advanced polymers.
• Biochemical Probe Development: Serves as a foundational component for designing fluorescent tags and molecular probes for biological imaging and diagnostics.
• Academic & Contract Research: A valuable reagent for methodological studies in organic chemistry and medicinal chemistry within R&D laboratories.

Basic Information

Product Name	1H-Indole-5-Carboxylic Acid,6-Fluoro
CAS No.	908600-73-7
Molecular Formula	C9H6FNO2
Molecular Weight	179.15 g/mol
Synonyms	6-Fluoro-1H-indole-5-carboxylic acid; 6-Fluoroindole-5-carboxylic acid; 5-Carboxy-6-fluoroindole; 6-Fluoro-5-indolecarboxylic acid; 6-F-5-IAA; 908600-73-7; 6-Fluoro-1H-indol-5-carbonsäure (German); Acide 6-fluoro-1H-indole-5-carboxylique (French)
EINECS	Contact for details

Quality Control

Our 1H-Indole-5-Carboxylic Acid,6-Fluoro is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with detailed specifications for trace metals, residual solvents, and related substances, supporting compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is sensitive to strong acids and organic solvents; keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.