Description

1H-Indole-5-Carboxylic Acid, 4-Fluoro- is a high-value fluorinated indole derivative, a crucial building block in modern synthetic organic chemistry. Its core value lies in its versatile indole scaffold modified with both carboxylic acid and fluorine functionalities, enabling precise molecular design and derivatization. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, especially in oncology, neurology, and anti-inflammatory therapies.
• Agrochemical Synthesis: Used in creating advanced pesticides and herbicides, where the fluorine atom enhances biological activity and metabolic stability.
• Material Science Research: Serves as a precursor for functional organic materials, including organic light-emitting diodes (OLEDs) and conductive polymers.
• Chemical Biology: Employed as a probe or labeling agent in biochemical research due to its reactive carboxylic acid group.
• Academic & R&D: A fundamental reagent for methodological studies in organic synthesis, particularly in cross-coupling and heterocyclic chemistry.

Basic Information

Product Name	1H-Indole-5-Carboxylic Acid, 4-Fluoro-
CAS No.	908600-72-6
Molecular Formula	C9H6FNO2
Molecular Weight	179.15 g/mol
Synonyms	4-Fluoro-1H-indole-5-carboxylic acid; 4-Fluoroindole-5-carboxylic Acid; 5-Carboxy-4-fluoroindole; 4-Fluoro-5-indolecarboxylic acid; 908600-72-6; 4-Fluoro-1H-indole-5-carboxylic acid; 4-Fluoro-1H-indol-5-carbonsäure (German)
EINECS	Contact for details

Quality Control

Our 1H-Indole-5-Carboxylic Acid, 4-Fluoro- is produced under stringent quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality parameters. Our commitment is to supply material that meets the exacting standards required for research and cGMP manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents, strong bases, and strong acids.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.