Description

1H-Indole-4-Carboxylic Acid, 5-Fluoro- is a high-value fluorinated indole derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its core value lies in enabling the precise construction of complex molecular architectures, particularly for pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors seeking to incorporate the unique properties of the fluorinated indole scaffold.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), especially in oncology, neurology, and anti-inflammatory drug discovery.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and plant growth regulators that leverage the biological activity of fluorinated heterocycles.
• Chemical Biology Probe: Serves as a precursor for fluorescent tags or molecular probes used to study biological pathways and protein interactions.
• Material Science: Potential monomer or precursor for specialty polymers and organic electronic materials due to the indole core's electronic properties.
• Academic & Contract Research: Fundamental reagent for methodological development in organic synthesis and catalysis research within universities and CROs.

Basic Information

Product Name	1H-Indole-4-Carboxylic Acid, 5-Fluoro-
CAS No.	908600-70-4
Molecular Formula	C9H6FNO2
Molecular Weight	179.15 g/mol
Synonyms	5-Fluoro-1H-indole-4-carboxylic acid; 5-Fluoroindole-4-carboxylic acid; 4-Carboxy-5-fluoroindole; 5-Fluoro-4-indolecarboxylic acid; 908600-70-4; 5-Fluoro-1H-indole-4-carboxylate
EINECS	Contact for details

Quality Control

Our 1H-Indole-4-Carboxylic Acid, 5-Fluoro- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the stringent requirements for research and development applications. Certificates of Analysis (COA) documenting all critical quality attributes are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.