Description

5-[(Chloroacetyl)Amino]-4-Cyano-N,N,3-Trimethylthiophene-2-Carboxamide is a high-purity, multi-functional organic intermediate of significant interest in advanced chemical synthesis. Its molecular architecture, featuring a thiophene core with chloroacetyl, cyano, and carboxamide substituents, makes it a versatile building block for constructing complex heterocyclic systems. This compound is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block in the research and synthesis of novel drug candidates, particularly those targeting specific enzyme inhibition or receptor modulation.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, or insecticides, leveraging its heterocyclic structure for bioactivity.
• Organic Light-Emitting Diode (OLED) Materials Research: Serves as a precursor for electron-transport or emissive layer materials due to its conjugated thiophene system and functional groups.
• Dye and Pigment Intermediate: Utilized in the synthesis of specialized dyes and pigments where the thiophene moiety contributes to color and stability properties.
• Chemical Research & Development: A valuable substrate for methodological studies in organic chemistry, including cross-coupling reactions and heterocycle functionalization.
• Material Science: Investigated as a monomer or additive for creating specialized polymers with unique electronic or thermal properties.

Basic Information

Product Name	5-[(Chloroacetyl)Amino]-4-Cyano-N,N,3-Trimethylthiophene-2-Carboxamide
CAS No.	908509-58-0
Molecular Formula	C12H14ClN3O2S
Molecular Weight	299.78 g/mol
Synonyms	5-[(Chloroacetyl)amino]-4-cyano-N,N,3-trimethyl-2-thiophenecarboxamide; 2-Thiophenecarboxamide, 5-[(chloroacetyl)amino]-4-cyano-N,N,3-trimethyl-; N-(5-Carbamoyl-4-cyano-3,6-dimethylthiophen-2-yl)-2-chloroacetamide; 908509-58-0; 5-(Chloroacetamido)-4-cyano-N,N,3-trimethylthiophene-2-carboxamide; Thiophene-2-carboxamide, 5-[(chloroacetyl)amino]-4-cyano-N,N,3-trimethyl-
EINECS	Contact for details

Quality Control

Our 5-[(Chloroacetyl)Amino]-4-Cyano-N,N,3-Trimethylthiophene-2-Carboxamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) is provided, detailing specifications such as assay (HPLC), related substances, and residual solvents. We support compliance with cGMP and ICH guidelines for pharmaceutical intermediates, and specifications can be aligned with client-specific requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from direct light exposure to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.