Description

4-Piperazin-1-Ylisoquinoline Dihydrochloride CAS NO 908292-89-7 is a high-purity, dihydrochloride salt derivative of a piperazinyl-substituted isoquinoline, a privileged scaffold in medicinal chemistry. This compound serves as a critical pharmaceutical intermediate and research chemical for the development of novel therapeutic agents. It is primarily utilized by pharmaceutical R&D organizations and contract research organizations (CROs) engaged in drug discovery programs.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to the versatile piperazine and isoquinoline pharmacophores.
• Biochemical Assay Development: Serves as a reference standard or ligand in high-throughput screening (HTS) assays to identify novel biological targets.
• Academic Research: Utilized in university and institutional labs for fundamental research in organic synthesis and heterocyclic chemistry.
• Chemical Biology Probes: Potential precursor for developing tool compounds to study specific enzyme or receptor functions.

Basic Information

Product Name	4-Piperazin-1-Ylisoquinoline Dihydrochloride
CAS No.	908292-89-7
Molecular Formula	C₁₃H₁₆N₃·2HCl
Molecular Weight	295.21 g/mol
Synonyms	4-(Piperazin-1-yl)isoquinoline dihydrochloride; 1-(Isoquinolin-4-yl)piperazine dihydrochloride; 4-(1-Piperazinyl)isoquinoline dihydrochloride; Isoquinoline, 4-(1-piperazinyl)-, dihydrochloride; 908292-89-7; 4-Piperazinylisoquinoline 2HCl
EINECS	Contact for details

Quality Control

Our 4-Piperazin-1-Ylisoquinoline Dihydrochloride is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with customer specifications and relevant research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.