Description

Tropine-3-Thiol Hydrochloride is a high-purity organic salt derivative of tropine, valued for its role as a key synthetic intermediate in advanced pharmaceutical research and development. Its functional thiol group makes it a versatile building block for constructing complex molecular architectures, particularly in the synthesis of active pharmaceutical ingredients (APIs) and specialized ligands. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors who require reliable, high-quality intermediates for process development and scale-up.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly those targeting the central nervous system.
• Chiral Ligand Synthesis: Used in the preparation of chiral ligands for asymmetric catalysis, enabling the production of enantiomerically pure compounds.
• Agrochemical Research: Serves as a precursor in the development of new pesticides and herbicides with specific biological activity.
• Chemical Biology Probes: Utilized in the creation of molecular probes for studying enzyme function and receptor interactions.
• Fine Chemical Synthesis: Employed in multi-step organic syntheses to introduce specific functional groups into complex molecules.
• Academic & Industrial R&D: A valuable reagent for methodological development and exploratory chemistry in research laboratories.

Basic Information

Product Name	Tropine-3-Thiol Hydrochloride
CAS No.	908266-48-8
Molecular Formula	C8H14ClNOS
Molecular Weight	207.72 g/mol
Synonyms	3-Mercaptotropane Hydrochloride; Tropan-3-thiol Hydrochloride; 8-Methyl-8-azabicyclo[3.2.1]octane-3-thiol Hydrochloride; 3-Thiotropine HCl; Tropine-3-thiol HCl; 3-Tropanethiol Hydrochloride
EINECS	Contact for details

Quality Control

Our Tropine-3-Thiol Hydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and purity, and is supplied with a detailed Certificate of Analysis (COA). We adhere to cGMP principles where applicable, ensuring the material meets the stringent requirements for use in pharmaceutical development and other critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and easily oxidized; for long-term storage, consider keeping under an inert atmosphere (e.g., nitrogen or argon) in a desiccator.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.