Description

5-Amino-3-Hydroxymethyl-1H-Indazole is a versatile and high-value heterocyclic building block, primarily utilized in advanced pharmaceutical and agrochemical research and development. Its molecular structure, featuring both amino and hydroxymethyl functional groups, makes it a critical intermediate for synthesizing complex bioactive molecules. This compound is essential for medicinal chemists and process development scientists working in drug discovery, particularly for creating targeted therapies.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, especially kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced crop protection agents and pesticides.
• Chemical Research & Development: Serves as a versatile building block in organic synthesis for creating new chemical entities and libraries.
• Material Science: Potential precursor for specialty polymers and advanced functional materials requiring indazole-based structures.
• Bioconjugation & Probe Development: Useful in the design of biochemical probes and diagnostic agents due to its reactive functional groups.

Basic Information

Product Name	5-Amino-3-Hydroxymethyl-1H-Indazole
CAS No.	908247-75-6
Molecular Formula	C8H9N3O
Molecular Weight	163.18 g/mol
Synonyms	1H-Indazole-5-amine, 3-(hydroxymethyl)-; 3-(Hydroxymethyl)-1H-indazol-5-amine; 5-Amino-3-hydroxymethylindazole; 5-Amino-3-(hydroxymethyl)-1H-indazole; 3-Hydroxymethyl-5-aminoindazole; 5-Amino-1H-indazole-3-methanol
EINECS	Contact for details

Quality Control

Our 5-Amino-3-Hydroxymethyl-1H-Indazole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide detailed Certificates of Analysis (COA) with every shipment to ensure traceability and compliance with your research or production specifications. Our quality commitment supports applications requiring high-purity chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.