Description

6,6-Dimethyl-3-(trifluoromethyl)-6,7-dihydro-1H-indazol-4(5H)-one is a high-value, fluorinated indazolone derivative serving as a critical advanced pharmaceutical intermediate. Its unique molecular scaffold, featuring a trifluoromethyl group, is engineered to enhance the metabolic stability, lipophilicity, and bioavailability of target drug candidates. This compound is primarily sought by pharmaceutical R&D and fine chemical synthesis teams for developing novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel small-molecule drugs, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, where the trifluoromethyl group can improve biological activity and environmental stability.
• Material Science Chemistry: Serves as a precursor for specialty chemicals and functional materials, including liquid crystals and organic electronic components.
• Medicinal Chemistry & SAR Studies: Employed in structure-activity relationship (SAR) studies to optimize the potency and selectivity of lead compounds.
• Contract Research & Manufacturing (CRO/CMO): Supplied to outsourcing partners for custom synthesis and process development projects.
• Academic Research: Utilized in university and institutional labs for heterocyclic chemistry research and the exploration of new synthetic methodologies.

Basic Information

Product Name	6,6-Dimethyl-3-(trifluoromethyl)-6,7-dihydro-1H-indazol-4(5H)-one
CAS No.	908111-34-2
Molecular Formula	C10H11F3N2O
Molecular Weight	232.20 g/mol
Synonyms	6,6-Dimethyl-3-(trifluoromethyl)-4,5,6,7-tetrahydro-1H-indazol-4-one; 4,5,6,7-Tetrahydro-6,6-dimethyl-3-(trifluoromethyl)-1H-indazol-4-one; 6,6-Dimethyl-3-trifluoromethyl-4,5,6,7-tetrahydro-1H-indazol-4-one; 3-Trifluoromethyl-6,6-dimethyl-4,5,6,7-tetrahydro-1H-indazol-4-one; 908111-34-2; 6,6-dimethyl-3-(trifluoromethyl)-4,7-dihydro-1H-indazol-4(5H)-one
EINECS	Contact for details

Quality Control

We supply 6,6-Dimethyl-3-(trifluoromethyl)-6,7-dihydro-1H-indazol-4(5H)-one in high-purity grades suitable for research and development. Our products undergo rigorous quality testing to ensure batch-to-batch consistency and compliance with stringent internal specifications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed to protect from moisture. For long-term storage, consider inert gas purging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.