Description

(S)-(5,6,7,8-Tetrahydroindolizin-8-Yl)Methanamine is a high-purity chiral amine building block of significant interest in advanced organic synthesis. This compound matters as a key intermediate for constructing complex nitrogen-containing heterocycles, which are core scaffolds in modern pharmaceutical discovery. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients. The compound is supplied with a Certificate of Analysis to ensure batch-to-batch consistency and reliability for critical synthetic applications.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the research and development of new drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the creation of novel, biologically active molecules for crop protection and pest management solutions.
• Asymmetric Catalysis: Serves as a precursor for chiral ligands or catalysts used in enantioselective synthesis.
• Chemical Research: Employed in academic and industrial R&D for exploring new synthetic methodologies and constructing complex molecular libraries.
• Fine Chemical Production: An intermediate in the multi-step synthesis of specialty chemicals and advanced materials.

Basic Information

Product Name	(S)-(5,6,7,8-Tetrahydroindolizin-8-Yl)Methanamine
CAS No.	908103-37-7
Molecular Formula	C9H16N2
Molecular Weight	152.24 g/mol
Synonyms	(8S)-8-(Aminomethyl)-5,6,7,8-tetrahydroindolizine; (S)-8-(Aminomethyl)-5,6,7,8-tetrahydroindolizine; (S)-Tetrahydroindolizin-8-ylmethanamine; (S)-Aminomethyltetrahydroindolizine; (S)-THIMA; (S)-Indolizidine-8-methanamine (enantiomer); Chiral Indolizidine Amine Building Block
EINECS	Contact for details

Quality Control

Our (S)-(5,6,7,8-Tetrahydroindolizin-8-Yl)Methanamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and chiral excess is provided with every shipment to guarantee traceability and performance consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.