Description

[2-(2,3-Dihydro-1H-Indol-3-Yl)-Ethyl]-Carbamic Acid tert-Butyl Ester is a high-purity, protected amine derivative of indoline, serving as a critical building block in advanced organic synthesis. Its core value lies in providing a versatile and stable intermediate for constructing complex nitrogen-containing heterocycles, which are central to modern pharmaceutical discovery. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries who require reliable, high-quality intermediates for API synthesis and novel compound library generation.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and oncological targets.
• Agrochemical Synthesis: Used in the creation of advanced crop protection agents and herbicides that require specific indoline-based scaffolds.
• Fine Chemical Production: Serves as a versatile precursor for synthesizing complex dyes, pigments, and specialty chemicals.
• Academic & Contract Research: A valuable reagent for medicinal chemistry programs and the construction of diverse heterocyclic compound libraries in academic and CRO settings.
• Peptidomimetics & PROTACs: Utilized in the design and synthesis of peptide mimics and proteolysis-targeting chimeras (PROTACs) due to its protected amine functionality.

Basic Information

Product Name	[2-(2,3-Dihydro-1H-Indol-3-Yl)-Ethyl]-Carbamic Acid tert-Butyl Ester
CAS No.	907969-24-8
Molecular Formula	C15H22N2O2
Molecular Weight	262.35 g/mol
Synonyms	N-Boc-2-(2,3-Dihydro-1H-indol-3-yl)ethylamine; tert-Butyl N-[2-(2,3-dihydro-1H-indol-3-yl)ethyl]carbamate; 3-[2-[(tert-Butoxycarbonyl)amino]ethyl]indoline; 2-(Indolin-3-yl)ethylcarbamic Acid tert-Butyl Ester; Boc-3-(2-aminoethyl)indoline; N-(tert-Butoxycarbonyl)-2-(indolin-3-yl)ethylamine; 907969-24-8; Boc-protected 3-(2-aminoethyl)indoline
EINECS	Contact for details

Quality Control

Our [2-(2,3-Dihydro-1H-Indol-3-Yl)-Ethyl]-Carbamic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring a reliable supply for research and development purposes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere such as nitrogen or argon to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.