Description

1H-Indole-1-Carboxylic Acid, 3-(1-Cyano-1-Methylethyl)-5-Methoxy-, 1,1-Dimethylethyl Ester is a high-purity, advanced pharmaceutical intermediate characterized by its complex indole-based molecular structure. This compound is critical for enabling sophisticated synthetic pathways in modern drug discovery and development. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the synthesis of novel therapeutic agents, particularly within oncology and central nervous system (CNS) research.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the multi-step synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new therapeutic molecules.
• Process Chemistry Development: Employed in scaling up synthetic routes from laboratory to pilot and commercial production scales.
• Contract Research & Manufacturing (CRAM): Supplied to organizations providing custom synthesis and process development services.
• Academic Research: Utilized in university and institutional labs for investigating novel heterocyclic chemistry and reaction methodologies.

Basic Information

Product Name	1H-Indole-1-Carboxylic Acid, 3-(1-Cyano-1-Methylethyl)-5-Methoxy-, 1,1-Dimethylethyl Ester
CAS No.	907602-77-1
Molecular Formula	C20H26N2O3
Molecular Weight	342.44 g/mol
Synonyms	tert-Butyl 3-(1-cyano-1-methylethyl)-5-methoxy-1H-indole-1-carboxylate; 3-(2-Cyano-2-propanyl)-5-methoxy-1H-indole-1-carboxylic acid 1,1-dimethylethyl ester; 5-Methoxy-3-(1-cyano-1-methylethyl)indole-1-carboxylic acid tert-butyl ester; 907602-77-1; tert-Butyl 5-methoxy-3-(2-cyano-2-propyl)-1H-indole-1-carboxylate; 1H-Indole-1-carboxylic acid, 3-(1-cyano-1-methylethyl)-5-methoxy-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our production of this high-value intermediate adheres to strict quality management systems, ensuring batch-to-batch consistency and traceability. Every lot is analyzed using advanced techniques including HPLC, GC, NMR, and mass spectrometry to confirm identity, purity, and the absence of critical impurities. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider maintaining the material under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.