Description

7-Bromo-1-Methylindoline-2,3-Dione is a versatile brominated isatin derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its value lies in providing a functionalized scaffold for constructing complex heterocyclic compounds and active pharmaceutical ingredients (APIs). This high-purity building block is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries engaged in drug discovery and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and oncological pathways.
• Agrochemical Research: Used in developing new active ingredients for crop protection products, leveraging its heterocyclic structure.
• Organic Synthesis Building Block: Employed in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic substitution reactions to introduce the 7-bromo moiety.
• Material Science: Potential monomer or precursor for creating functional organic materials and dyes.
• Academic & R&D: Serves as a standard reagent in university and corporate research laboratories for methodological studies and novel compound library generation.

Basic Information

Product Name	7-Bromo-1-Methylindoline-2,3-Dione
CAS No.	906660-35-3
Molecular Formula	C9H6BrNO2
Molecular Weight	240.05 g/mol
Synonyms	7-Bromo-1-methylisatin; 7-Bromo-1-methyl-1H-indole-2,3-dione; 1-Methyl-7-bromoisatin; 7-Bromo-1-methylindole-2,3-dione; 906660-35-3; 7-Bromo-1-methyl-2,3-dioxoindoline
EINECS	Contact for details

Quality Control

Our 7-Bromo-1-Methylindoline-2,3-Dione is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications. Our quality commitment supports applications requiring high-purity intermediates for regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials. Due to its light-sensitive nature, handling should minimize prolonged exposure to light.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.