Description

4-(Tetrahydropyran-4-Yloxy)Benzyl Bromide is a high-purity organic bromide building block of significant synthetic utility. This compound is valued for its role as a key intermediate in the development of complex pharmaceutical molecules and advanced materials. It is primarily sought by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging its benzyl bromide functionality for molecular diversification.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis and transition metal catalysis.
• Material Science Research: Employed in the synthesis of functionalized polymers, liquid crystals, and organic electronic materials due to its reactive benzylic position and ether linkage.
• Chemical Biology Probes: Useful for the preparation of molecular probes and tags for studying biological systems and protein interactions.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client projects.

Basic Information

Product Name	4-(Tetrahydropyran-4-Yloxy)Benzyl Bromide
CAS No.	906352-72-5
Molecular Formula	C13H17BrO2
Molecular Weight	285.18 g/mol
Synonyms	4-((Tetrahydro-2H-pyran-4-yl)oxy)benzyl bromide; 4-(Oxan-4-yloxy)benzyl bromide; (4-(Oxan-4-yloxy)phenyl)methanol, bromide; 4-(Tetrahydropyran-4-yloxy)benzyl bromide; Benzyl bromide, 4-((tetrahydro-2H-pyran-4-yl)oxy)-; 906352-72-5; THP-OBn-Br
EINECS	Contact for details

Quality Control

Our 4-(Tetrahydropyran-4-Yloxy)Benzyl Bromide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.