Description

2,5-Pyrrolidinedione, 3-(5,6-Dihydro-4H-Pyrrolo[3,2,1-Ij]Quinolin-1-Yl)-4-(1H-Indol-3-Yl)-, (3S,4S)- is a high-purity, stereochemically defined advanced pharmaceutical intermediate. This compound is critical for the research and development of novel therapeutic agents, particularly in the field of oncology and central nervous system (CNS) disorders. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers requiring a reliable supply of complex, chiral building blocks for drug synthesis.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of investigational new drugs (INDs) and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies and the development of targeted small-molecule inhibitors.
• Oncology Drug Development: Used in the synthesis of potential anti-cancer compounds due to its fused heterocyclic structure.
• CNS-Active Compound Synthesis: Employed in creating novel candidates for treating neurological and psychiatric conditions.
• Process Chemistry & Scale-Up: Provides a defined starting point for optimizing synthetic routes from laboratory to pilot plant scale.
• Contract Research & Manufacturing (CRAM): Supplied to organizations specializing in custom synthesis and development services.

Basic Information

Product Name	2,5-Pyrrolidinedione, 3-(5,6-Dihydro-4H-Pyrrolo[3,2,1-Ij]Quinolin-1-Yl)-4-(1H-Indol-3-Yl)-, (3S,4S)-
CAS No.	905854-03-7
Molecular Formula	C23H19N3O2
Molecular Weight	369.42 g/mol
Synonyms	(3S,4S)-3-(5,6-Dihydro-4H-pyrrolo[3,2,1-ij]quinolin-1-yl)-4-(1H-indol-3-yl)pyrrolidine-2,5-dione; (3S,4S)-4-(1H-Indol-3-yl)-3-(5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-1-yl)pyrrolidine-2,5-dione; 905854-03-7; (3S,4S)- enantiomer of the fused quinoline-indole pyrrolidinedione derivative
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is characterized using advanced analytical techniques to confirm identity, purity, and stereochemical integrity. Certificates of Analysis (COA) are available upon request, detailing specifications such as chiral purity, chemical purity (HPLC), and residual solvent levels. Our quality system is designed to support cGMP requirements for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is light-sensitive and should be handled under appropriate conditions to maintain stability. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% de
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.