Description

2,4,6-Tri-o-Acetyl-3-o-Allyl-D-Glucopyranosyl Trichloroacetimidate is a high-purity, advanced glycosyl donor used in stereoselective glycosylation reactions. This compound is critical for the efficient synthesis of complex oligosaccharides and glycoconjugates, offering excellent reactivity and selectivity. It is an essential building block for researchers and manufacturers in pharmaceutical development, particularly for creating novel carbohydrate-based drugs, vaccines, and diagnostic agents.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of complex carbohydrate-based active pharmaceutical ingredients (APIs) and prodrugs.
• Glycoconjugate Synthesis: Used in the preparation of glycoproteins, glycolipids, and other biologically active glycoconjugates for therapeutic and diagnostic applications.
• Oligosaccharide Assembly: Enables the stereocontrolled construction of specific glycosidic linkages in automated and manual oligosaccharide synthesis.
• Glycoscience Research: A vital reagent for academic and industrial research exploring carbohydrate-protein interactions, cell signaling, and immunology.
• Vaccine Development: Employed in the synthesis of carbohydrate antigens for conjugate vaccine candidates against bacterial and viral pathogens.
• Process Development: Serves as a critical starting material for scaling up the production of carbohydrate-based therapeutics under GMP conditions.

Basic Information

Product Name	2,4,6-Tri-o-Acetyl-3-o-Allyl-D-Glucopyranosyl Trichloroacetimidate
CAS No.	905714-81-0
Molecular Formula	C17H22Cl3NO9
Molecular Weight	490.72 g/mol
Synonyms	3-O-Allyl-2,4,6-tri-O-acetyl-α-D-glucopyranosyl trichloroacetimidate; 1-[(2R,3R,4S,5R,6R)-3-Allyl-4,5-diacetoxy-6-(acetoxymethyl)oxan-2-yl]-2,2,2-trichloroethanimidate; Allyl 2,4,6-tri-O-acetyl-3-O-allyl-α-D-glucopyranoside Trichloroacetimidate; Glycosyl Donor 905714-81-0; Trichloroacetimidate Glycosylation Reagent; Acetylated Allyl Glucoside Trichloroacetimidate
EINECS	Contact for details

Quality Control

Our 2,4,6-Tri-o-Acetyl-3-o-Allyl-D-Glucopyranosyl Trichloroacetimidate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chemical purity suitable for research and process development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support development projects requiring material that meets stringent analytical standards for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and reactivity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 0.5%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.