Description

5-Iodo-2,3-Dihydro-1H-Isoindole is a high-value halogenated isoindoline derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its unique structure, featuring a fused bicyclic ring system with an iodine substituent, makes it a versatile building block for constructing complex molecular architectures. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for applications in medicinal chemistry, ligand synthesis, and material science.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and oncology targets.
• Agrochemical Research: Used in the development of new active ingredients for crop protection and pest management.
• Ligand & Catalyst Development: Serves as a scaffold for creating specialized ligands in transition metal catalysis and organometallic chemistry.
• Material Science: Building block for organic electronic materials, such as charge-transport layers or photoactive components.
• Chemical Biology: Useful as a probe or tag in bioconjugation and target identification studies due to the reactivity of the iodine atom.
• Academic & Contract Research: Employed in fundamental organic synthesis research and by CROs (Contract Research Organizations) for client projects.

Basic Information

Product Name	5-Iodo-2,3-Dihydro-1H-Isoindole
CAS No.	905274-25-1
Molecular Formula	C8H8IN
Molecular Weight	245.06 g/mol
Synonyms	5-Iodoisoindoline; 2,3-Dihydro-5-iodo-1H-isoindole; 5-Iodo-1H-isoindoline; 5-Iodoisoindoline; 1H-Isoindole, 5-iodo-2,3-dihydro-; 905274-25-1; 5-Iodo-2,3-dihydroisoindole
EINECS	Contact for details

Quality Control

Our 5-Iodo-2,3-Dihydro-1H-Isoindole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.