Description

Isopropyl 2-Amino-5-Methyl-4-(4-Propylphenyl)-Thiophene-3-Carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its specific thiophene-carboxylate structure. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs) where precise molecular architecture is required for target binding and efficacy. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, particularly in areas requiring sophisticated heterocyclic chemistry.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, or metabolic diseases.
• Organic Synthesis Research: Used in academic and industrial R&D laboratories for constructing complex thiophene-based molecular libraries for high-throughput screening.
• Agrochemical Development: Acts as a precursor in the research and development of new generation pesticides and herbicides that leverage its heterocyclic core.
• Material Science Precursor: Investigated for use in the synthesis of organic semiconductors and conductive polymers due to the electron-rich thiophene moiety.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP guidelines.

Basic Information

Product Name	Isopropyl 2-Amino-5-Methyl-4-(4-Propylphenyl)-Thiophene-3-Carboxylate
CAS No.	905011-49-6
Molecular Formula	C18H23NO2S
Molecular Weight	317.44 g/mol
Synonyms	2-Amino-5-methyl-4-(4-propylphenyl)thiophene-3-carboxylic acid isopropyl ester; Isopropyl 2-amino-5-methyl-4-(p-propylphenyl)thiophene-3-carboxylate; 4-(4-Propylphenyl)-2-amino-5-methylthiophene-3-carboxylic acid isopropyl ester; 905011-49-6; Thiophene-3-carboxylic acid, 2-amino-5-methyl-4-[4-(1-methylethyl)phenyl]-, isopropyl ester (related); API Intermediate 905011-49-6
EINECS	Contact for details

Quality Control

Our Isopropyl 2-Amino-5-Methyl-4-(4-Propylphenyl)-Thiophene-3-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure compliance with stringent industry standards for pharmaceutical intermediates. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.