Description

4-Chloro-5-Fluoroindoline is a high-purity, multi-functional heterocyclic building block of significant importance in advanced organic synthesis. Its core value lies in its fused indoline structure, which is halogenated at strategic positions, making it a critical intermediate for constructing complex molecular architectures. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly for central nervous system (CNS) and oncology targets.
• Agrochemical Synthesis: Serves as a building block for creating advanced herbicides, fungicides, and insecticides with enhanced efficacy.
• Material Science Research: Used in the development of organic electronic materials, such as dyes and pigments, due to its electron-rich indoline core.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and enzyme functions.
• Catalyst Ligand Precursor: The halogenated indoline structure can be modified to create novel ligands for transition metal catalysis.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects requiring complex, halogenated heterocycles.

Basic Information

Product Name	4-Chloro-5-Fluoroindoline
CAS No.	903551-32-6
Molecular Formula	C8H7ClFN
Molecular Weight	171.60 g/mol
Synonyms	4-Chloro-5-fluoro-2,3-dihydro-1H-indole; 5-Fluoro-4-chloroindoline; 1H-Indole, 4-chloro-5-fluoro-2,3-dihydro-; 4-Chloro-5-fluoro-2,3-dihydroindole; 903551-32-6; 4-Cl-5-F-indoline
EINECS	Contact for details

Quality Control

Our 4-Chloro-5-Fluoroindoline is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC purity, NMR, and mass spectrometry confirmation. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available for every batch upon request, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.