Description

4,6-Dichloro-2,3-Dihydro-1H-Indole Hydrochloride is a high-purity, synthetically valuable organic intermediate. This compound is essential for the development of novel active pharmaceutical ingredients (APIs) and advanced agrochemicals, serving as a key building block in heterocyclic chemistry. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors for synthesis and process development.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used as a building block for developing new herbicides, fungicides, and insecticides with enhanced efficacy.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, dyes, and other advanced organic materials.
• Academic Research: Utilized in university and institutional labs for studying heterocyclic reaction mechanisms and developing new synthetic methodologies.

Basic Information

Product Name	4,6-Dichloro-2,3-Dihydro-1H-Indole Hydrochloride
CAS No.	903551-23-5
Molecular Formula	C8H8Cl3N
Molecular Weight	240.51 g/mol
Synonyms	4,6-Dichloroindoline Hydrochloride; 4,6-Dichloro-2,3-dihydro-1H-indole HCl; 1H-Indole, 4,6-dichloro-2,3-dihydro-, hydrochloride; 4,6-Dichloroindoline HCl; 4,6-Dichloro-2,3-dihydroindole Hydrochloride; 4,6-Dichloro-2,3-dihydro-1H-indole Hydrochloride Salt
EINECS	Contact for details

Quality Control

Our 4,6-Dichloro-2,3-Dihydro-1H-Indole Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.