Description

1-[2-(3,4-Dihydroisoquinolin-2(1H)-Yl)-4-Methylpyrimidin-5-Yl]Ethanone is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is of significant value for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and manufacturers in the pharmaceutical and biotechnology sectors engaged in drug discovery and development programs.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of potential drug candidates targeting central nervous system (CNS) disorders, oncology, or other therapeutic areas.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new chemical entities with improved efficacy and safety profiles.
• API Development: Serves as a core scaffold for constructing complex molecules in the development of new active pharmaceutical ingredients.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services for the pharmaceutical industry.
• Biochemical Research: May be utilized as a tool compound or a ligand in biochemical assays to study enzyme inhibition or receptor binding.

Basic Information

Product Name	1-[2-(3,4-Dihydroisoquinolin-2(1H)-Yl)-4-Methylpyrimidin-5-Yl]Ethanone
CAS No.	903475-61-6
Molecular Formula	C₁₆H₁₇N₃O
Molecular Weight	267.33 g/mol
Synonyms	1-[2-(3,4-Dihydro-1H-isoquinolin-2-yl)-4-methylpyrimidin-5-yl]ethanone; 5-Acetyl-2-(1,2,3,4-tetrahydroisoquinolin-2-yl)-4-methylpyrimidine; Ethanone, 1-[2-(3,4-dihydro-1H-isoquinolin-2-yl)-4-methyl-5-pyrimidinyl]-; 903475-61-6; 2-(3,4-Dihydroisoquinolin-2(1H)-yl)-4-methyl-5-acetylpyrimidine
EINECS	Contact for details

Quality Control

Our 1-[2-(3,4-Dihydroisoquinolin-2(1H)-Yl)-4-Methylpyrimidin-5-Yl]Ethanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) documenting batch-specific results are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to ensure stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.