Description

tert-Butyl 4-(Benzyloxy)-1H-Indole-1-Carboxylate is a high-purity, protected indole derivative that serves as a critical synthetic intermediate in advanced organic chemistry. This compound is valued for its role in constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of novel active compounds.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, especially those targeting neurological and oncological pathways.
• Agrochemical Research: Used in the development of new pesticides and herbicides where the indole scaffold is a core structural motif.
• Organic Synthesis: Serves as a versatile precursor for introducing the protected 4-benzyloxyindole moiety into more complex molecules via further functionalization.
• Academic & Contract Research: Essential for medicinal chemistry programs in universities and CROs (Contract Research Organizations) exploring structure-activity relationships (SAR).
• Peptidomimetics Development: Utilized in the design and synthesis of peptidomimetics and other biologically active molecules that incorporate modified tryptophan analogs.

Basic Information

Product Name	tert-Butyl 4-(Benzyloxy)-1H-Indole-1-Carboxylate
CAS No.	903131-59-9
Molecular Formula	C20H21NO3
Molecular Weight	323.39 g/mol
Synonyms	1H-Indole-1-carboxylic acid, 4-(phenylmethoxy)-, 1,1-dimethylethyl ester; 4-(Benzyloxy)-1H-indole-1-carboxylic acid tert-butyl ester; tert-Butyl 4-benzyloxyindole-1-carboxylate; Boc-4-benzyloxyindole; 4-Benzyloxyindole-1-N-Boc; 1-Boc-4-benzyloxyindole; N-Boc-4-(benzyloxy)indole; 903131-59-9
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-(Benzyloxy)-1H-Indole-1-Carboxylate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, suitable for demanding research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be opaque or stored in dark conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.