Description

5-Formyl-2-(trifluoromethyl)-1,3-thiazole is a versatile and highly functionalized heterocyclic building block. Its unique structure, featuring both an aldehyde group and a trifluoromethyl-substituted thiazole core, makes it a critical intermediate for synthesizing complex molecules with tailored properties. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries. It enables the efficient construction of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in antiviral, anticancer, and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the development of advanced pesticides, herbicides, and fungicides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Material Science Research: Serves as a precursor for functionalized polymers, liquid crystals, and organic electronic materials due to its electron-withdrawing characteristics.
• Chemical Biology & Proteomics: The reactive aldehyde group allows for use as a labeling agent or linker in bioconjugation and probe development.
• Custom Synthesis & Contract Manufacturing: An essential starting material for custom synthesis projects requiring the introduction of a thiazole moiety with specific functionality.

Basic Information

Product Name	5-Formyl-2-(trifluoromethyl)-1,3-thiazole
CAS No.	903130-38-1
Molecular Formula	C5H2F3NOS
Molecular Weight	181.14 g/mol
Synonyms	2-(Trifluoromethyl)-1,3-thiazole-5-carboxaldehyde; 2-(Trifluoromethyl)-5-formylthiazole; 5-Formyl-2-trifluoromethylthiazole; 1,3-Thiazole-5-carboxaldehyde, 2-(trifluoromethyl)-; 2-Trifluoromethylthiazole-5-carbaldehyde; 5-Thiazolecarboxaldehyde, 2-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 5-Formyl-2-(trifluoromethyl)-1,3-thiazole is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP standards for pharmaceutical applications and can tailor quality protocols to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is easily oxidized and should be handled under an inert atmosphere for long-term storage or when opening a new container. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.