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[7-Fluoro-2-(4-Fluoro-Phenyl)-1H-Indol-3-Yl]-Acetic Acid CAS NO 901194-06-7


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CAS No.:901194-06-7

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

[7-Fluoro-2-(4-Fluoro-Phenyl)-1H-Indol-3-Yl]-Acetic Acid is a high-purity fluorinated indole acetic acid derivative, serving as a critical advanced pharmaceutical intermediate. Its value lies in its precise molecular architecture, which is essential for the synthesis of novel active pharmaceutical ingredients (APIs) with targeted therapeutic effects. This compound is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of next-generation drugs, particularly in oncology and central nervous system (CNS) research.

Application

  • Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially in oncology and CNS therapeutic areas.
  • Research & Development (R&D): Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
  • Active Pharmaceutical Ingredient (API) Synthesis: Serves as a core scaffold in multi-step synthetic routes for complex target molecules.
  • Biochemical Research: Potential tool compound for studying biological pathways involving indole-based signaling molecules.
  • Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP production of clinical trial materials.

Basic Information

Product Name [7-Fluoro-2-(4-Fluoro-Phenyl)-1H-Indol-3-Yl]-Acetic Acid
CAS No. 901194-06-7
Molecular Formula C16H11F2NO2
Molecular Weight 287.26 g/mol
Synonyms 2-[7-Fluoro-2-(4-fluorophenyl)-1H-indol-3-yl]acetic acid; 7-Fluoro-2-(4-fluorophenyl)-1H-indole-3-acetic acid; 2-(7-Fluoro-2-(4-fluorophenyl)-1H-indol-3-yl)acetic acid; 1H-Indole-3-acetic acid, 7-fluoro-2-(4-fluorophenyl)-; F2FIA; (7-Fluoro-2-(4-fluorophenyl)-1H-indol-3-yl)acetic acid
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Quality Control

Our [7-Fluoro-2-(4-Fluoro-Phenyl)-1H-Indol-3-Yl]-Acetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and batch-to-batch consistency suitable for pharmaceutical R&D. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorinating agents. For long-term storage, consider storage under an inert atmosphere.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (HPLC) Conforms
Identification (IR) Conforms
Purity (HPLC) ≥ 98.0%
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%
Single Unknown Impurity (HPLC) ≤ 0.5%
Total Impurities (HPLC) ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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