Description

2-Amino-4-(2,5-Dichlorophenyl)-3-Thiophenecarbonitrile is a high-value, multi-functional heterocyclic building block with a complex molecular architecture. Its core value lies in its versatility as a key synthetic intermediate for constructing advanced organic molecules, particularly in pharmaceutical research and development. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its thiophene and nitrile functionalities.
• Material Science: Acts as a building block for organic semiconductors, conductive polymers, and non-linear optical (NLO) materials due to its electron-rich thiophene core.
• Dye & Pigment Synthesis: Employed in the creation of specialized dyes and pigments where the dichlorophenyl and aminothiophene groups impart specific color and stability properties.
• Ligand & Catalyst Development: Useful for constructing complex chelating ligands in coordination chemistry and catalysis.
• Academic & Contract Research: A valuable reagent for universities and CROs (Contract Research Organizations) exploring new chemical spaces and reaction methodologies.

Basic Information

Product Name	2-Amino-4-(2,5-Dichlorophenyl)-3-Thiophenecarbonitrile
CAS No.	901184-30-3
Molecular Formula	C11H6Cl2N2S
Molecular Weight	269.15 g/mol
Synonyms	2-Amino-4-(2,5-dichlorophenyl)thiophene-3-carbonitrile; 3-Thiophenecarbonitrile, 2-amino-4-(2,5-dichlorophenyl)-; 4-(2,5-Dichlorophenyl)-2-aminothiophene-3-carbonitrile; 2-Amino-4-(2,5-dichlorophenyl)-3-cyanothiophene; 901184-30-3; AKOS005258065; AS-64133; SCHEMBL1884256; ZINC000253899793
EINECS	Contact for details

Quality Control

Our 2-Amino-4-(2,5-Dichlorophenyl)-3-Thiophenecarbonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.