Description

2-tert-Butyl-1H-Indole-5-Carbonitrile is a high-value, synthetically versatile indole derivative, serving as a critical building block in advanced organic synthesis. Its unique molecular architecture, featuring both a sterically hindered tert-butyl group and a reactive nitrile functionality, makes it an indispensable intermediate for creating complex molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and inflammation.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, leveraging its indole core for biological activity.
• Material Science: Serves as a monomer or functional additive in the research of advanced polymers, liquid crystals, and organic electronic materials.
• Chemical Synthesis: Acts as a versatile scaffold for further functionalization, enabling the creation of libraries of compounds for high-throughput screening (HTS).
• Academic & Contract Research: Essential for fundamental organic chemistry research and process development in contract research organizations (CROs).

Basic Information

Product Name	2-tert-Butyl-1H-Indole-5-Carbonitrile
CAS No.	900640-47-3
Molecular Formula	C₁₃H₁₄N₂
Molecular Weight	198.27 g/mol
Synonyms	2-tert-Butyl-1H-indole-5-carbonitrile; 5-Cyano-2-tert-butylindole; 2-(1,1-Dimethylethyl)-1H-indole-5-carbonitrile; 2-tert-Butylindole-5-carbonitrile; 2-tert-Butyl-5-cyanoindole; 900640-47-3; tert-Butyl indole carbonitrile
EINECS	Contact for details

Quality Control

Our 2-tert-Butyl-1H-Indole-5-Carbonitrile is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the exacting standards required for research and development. A detailed Certificate of Analysis (COA) is provided with each shipment, guaranteeing traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.