Description

3-(5-Bromothiophen-2-Yl)Propanoic Acid is a high-purity brominated thiophene derivative, serving as a critical building block in advanced organic synthesis. Its value lies in providing a functionalized aromatic core with a reactive carboxylic acid group, enabling precise molecular construction for complex target compounds. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for candidates targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging the thiophene moiety for bioactivity.
• Material Science Research: Employed as a monomer or functional unit in the development of conductive polymers, organic semiconductors, and advanced organic frameworks.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands for metal catalysis and organocatalysts.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and enzyme mechanisms.
• Custom Synthesis and Contract Manufacturing: A fundamental building block for custom synthesis projects and scale-up production under cGMP or ISO standards.

Basic Information

Product Name	3-(5-Bromothiophen-2-Yl)Propanoic Acid
CAS No.	900027-23-8
Molecular Formula	C7H7BrO2S
Molecular Weight	235.10 g/mol
Synonyms	5-Bromo-2-thiophenepropanoic Acid; 3-(5-Bromo-2-thienyl)propanoic Acid; 2-Thiophenepropanoic Acid, 5-bromo-; β-(5-Bromothiophen-2-yl)propionic Acid; 900027-23-8; 5-Bromothiophene-2-propionic Acid; 3-(5-Bromo-2-thiophenyl)propanoic Acid
EINECS	Contact for details

Quality Control

Our production of 3-(5-Bromothiophen-2-Yl)Propanoic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including HPLC, NMR, and GC-MS to verify identity, potency, and impurity profiles. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support development and commercial projects requiring compliance with ISO, GMP, and REACH standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere or in a desiccator after opening to prevent degradation. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.