Description

(E)-3-(2-Methoxyphenyl)-2-[(1-Methyl-1H-Pyrrol-2-Yl)Carbonyl]-2-Propenenitrile is a high-purity, advanced pharmaceutical intermediate characterized by its unique molecular architecture. This compound is critical for the synthesis of complex organic molecules, offering a versatile building block for research and development. It is primarily utilized by pharmaceutical, agrochemical, and fine chemical manufacturers engaged in the development of novel active ingredients. Its precise structure enables key chemical transformations essential for creating targeted molecular scaffolds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Serves as a building block for developing new-generation pesticides and herbicides with specific modes of action.
• Material Science: Used in the research and development of specialty polymers and organic electronic materials.
• Chemical Synthesis: Acts as a versatile synthon in organic chemistry for constructing complex heterocyclic compounds and natural product analogs.
• Academic & Contract Research: Essential for medicinal chemistry programs and process development in university and CRO (Contract Research Organization) laboratories.

Basic Information

Product Name	(E)-3-(2-Methoxyphenyl)-2-[(1-Methyl-1H-Pyrrol-2-Yl)Carbonyl]-2-Propenenitrile
CAS No.	900019-51-4
Molecular Formula	C16H14N2O2
Molecular Weight	266.30 g/mol
Synonyms	(E)-3-(2-Methoxyphenyl)-2-(1-methyl-1H-pyrrole-2-carbonyl)acrylonitrile; 2-Propenenitrile, 3-(2-methoxyphenyl)-2-[(1-methyl-1H-pyrrol-2-yl)carbonyl]-, (2E)-; (E)-3-(o-Methoxyphenyl)-2-(N-methylpyrrole-2-carbonyl)acrylonitrile; Light-sensitive acrylonitrile derivative
EINECS	Contact for details

Quality Control

Every batch of (E)-3-(2-Methoxyphenyl)-2-[(1-Methyl-1H-Pyrrol-2-Yl)Carbonyl]-2-Propenenitrile is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency meet the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in light-resistant secondary packaging.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5% w/w

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.