Description

3-(5-Methoxy-1H-Indol-2-Yl)-2-(Methylsulfonyl)Acrylonitrile is a specialized indole-based acrylonitrile derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its unique molecular architecture, featuring both an electron-rich indole moiety and a reactive methylsulfonyl-acrylonitrile group, makes it a valuable building block for constructing complex heterocyclic systems. This high-purity compound is essential for research and development chemists in the pharmaceutical and agrochemical sectors, particularly for the synthesis of novel active ingredients targeting specific biological pathways.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting neurological and oncological pathways.
• Agrochemical Research: Used in the development of new herbicides and fungicides, leveraging its heterocyclic structure for bioactivity.
• Chemical Biology Probe Synthesis: Employed to create molecular probes for studying enzyme function and protein interactions.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of advanced polymers with specific electronic or optical properties.
• Academic & Industrial R&D: A versatile building block for methodological development in organic synthesis and medicinal chemistry.

Basic Information

Product Name	3-(5-Methoxy-1H-Indol-2-Yl)-2-(Methylsulfonyl)Acrylonitrile
CAS No.	900014-99-5
Molecular Formula	C₁₅H₁₄N₂O₃S
Molecular Weight	302.35 g/mol
Synonyms	2-(Methylsulfonyl)-3-(5-methoxy-1H-indol-2-yl)acrylonitrile; 3-(5-Methoxy-1H-indol-2-yl)-2-(methylsulfonyl)-2-propenenitrile; (E/Z)-3-(5-Methoxy-1H-indol-2-yl)-2-(methylsulfonyl)acrylonitrile; 900014-99-5; Methylsulfonyl acrylonitrile indole derivative
EINECS	Contact for details

Quality Control

Our production of 3-(5-Methoxy-1H-Indol-2-Yl)-2-(Methylsulfonyl)Acrylonitrile adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity, critical for sensitive R&D applications. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive and should be handled under appropriate conditions to maintain stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.