Description

5-Bromo-1-Methylindoline is a versatile brominated indoline derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its value lies in providing a functionalized scaffold for constructing complex molecules, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists working in pharmaceutical, agrochemical, and advanced material sectors who require high-purity building blocks for heterocyclic synthesis.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the research and development of new active ingredients for crop protection products.
• Material Science Research: Serves as a precursor for organic electronic materials and functional dyes due to its indoline core.
• Chemical Biology Probes: Utilized in the development of molecular probes and tags for studying biological systems.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological development and novel heterocycle synthesis.
• Fine Chemical Production: Intermediate in multi-step syntheses of complex, high-value specialty chemicals.

Basic Information

Product Name	5-Bromo-1-Methylindoline
CAS No.	99848-78-9
Molecular Formula	C9H10BrN
Molecular Weight	212.09 g/mol
Synonyms	1-Methyl-5-bromoindoline; 5-Bromo-1-methyl-2,3-dihydro-1H-indole; 5-Bromo-N-methylindoline; 99848-78-9; 1H-Indole, 5-bromo-2,3-dihydro-1-methyl-; 5-Bromo-1-methyl-2,3-dihydroindole
EINECS	Contact for details

Quality Control

Our 5-Bromo-1-Methylindoline is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to verify identity and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We adhere to cGMP principles where applicable to support our customers in regulated development pipelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed when not in use to minimize exposure to air and moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.